| Long name |
FOXG1/BF-1 Polyclonal Antibody, Biotin Conjugated |
| Category |
Conjugated Primary Antibodies |
| Conjugation |
Biotin |
| Host Organism |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen |
FOXG1/BF-1 |
| Specificity |
This is a highly specific antibody against FOXG1/BF-1. |
| Modification |
Unmodified |
| Modification site |
None |
| Clonality |
Polyclonal |
| Clone |
Polyclonal antibody |
| Concentration |
1ug per 1ul |
| Source |
KLH conjugated synthetic peptide derived from human FOXG1 |
| Tested applications |
WB, IHC-P |
| Recommended dilutions |
WB(1:100-1000), IHC-P(1:100-500) |
| Crossreactivity |
Human, Mouse, Rat |
| Crossreactive species details |
Due to limited amount of testing and knowledge, not every possible cross-reactivity is known. |
| Antigen background |
The winged-helix transcriptional repressor (WH) BF-1 gene encodes brain factor 1 (BF-1), also known as foxg1, and is essential for the proliferation of progenitor cells in the cerebral cortex and influences regional patterning in the mammalian telencephalon (1–4). WH proteins are a family of putative transcriptional regulators with diverse roles in development, and are characterized by a highly conserved DNA binding structure, the WH domain (1,5,6). BF-1 plays a critical role in the development of the cerebral hemispheres of the brain and targeted disruption of the gene leads to severe defects in the development of telencephalic structures, such as the cerebral cortex and basal ganglia (1). The loss of BF-1 results in an accelerated rate of neuronal differentiation and the shortening of the neurogenetic period in the embryonic cerebral cortex (1,7). BF-1 is expressed by E8.5 in telencephalic progenitors (1). It may also regulate the response of cerebral cortical progenitors to environmental cues (1). |
| Purification method |
This antibody was purified via Protein A. |
| Storage conditions |
Keep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year. |
| Excitation Emission |
N/A |
| Synonyms |
BF 1; BF 2; BF-1; BF-2; BF1; BF2 ; Brain factor 1; Brain factor 2; FHKL; FKH2; FKHL1; FKHL2; FKHL2; FKHL3; FKHL4; Forkhead box G1A; Forkhead box G1B; Forkhead box protein G1; Forkhead box protein G1A; Forkhead box protein G1B; Forkhead box protein G1C; Forkhead drosophila homolog like 2; Forkhead like 1; Forkhead like 2; FOXG1_HUMAN. |
| Properties |
If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.Biotin conjugates can be detected by horseradish peroxidase, alkaline phosphatase substrates or anti biotin conjugated antibodies. Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA. To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1.6. |
| Additional conjugation |
Biotinylated |
| French translation |
anticorps |