FOXG1/BF-1 Antibody, HRP Conjugated

General information

Catalog numberbs-11557R-HRP
NameFOXG1/BF-1 Antibody, HRP Conjugated
Price€ 350.00
Size0.1ml


Details

Long nameFOXG1/BF-1 Polyclonal Antibody, HRP Conjugated
CategoryConjugated Primary Antibodies
ConjugationHRP
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenFOXG1/BF-1
SpecificityThis is a highly specific antibody against FOXG1/BF-1.
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human FOXG1
Tested applicationsWB, IHC-P
Recommended dilutionsWB(1:100-1000), IHC-P(1:100-500)
CrossreactivityHuman, Mouse, Rat
Crossreactive species detailsDue to limited amount of testing and knowledge, not every possible cross-reactivity is known.
Antigen backgroundThe winged-helix transcriptional repressor (WH) BF-1 gene encodes brain factor 1 (BF-1), also known as foxg1, and is essential for the proliferation of progenitor cells in the cerebral cortex and influences regional patterning in the mammalian telencephalon (1–4). WH proteins are a family of putative transcriptional regulators with diverse roles in development, and are characterized by a highly conserved DNA binding structure, the WH domain (1,5,6). BF-1 plays a critical role in the development of the cerebral hemispheres of the brain and targeted disruption of the gene leads to severe defects in the development of telencephalic structures, such as the cerebral cortex and basal ganglia (1). The loss of BF-1 results in an accelerated rate of neuronal differentiation and the shortening of the neurogenetic period in the embryonic cerebral cortex (1,7). BF-1 is expressed by E8.5 in telencephalic progenitors (1). It may also regulate the response of cerebral cortical progenitors to environmental cues (1).
Purification methodThis antibody was purified via Protein A.
Storage conditionsKeep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% Gentamicin. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
Excitation EmissionN/A
SynonymsBF 1; BF 2; BF-1; BF-2; BF1; BF2 ; Brain factor 1; Brain factor 2; FHKL; FKH2; FKHL1; FKHL2; FKHL2; FKHL3; FKHL4; Forkhead box G1A; Forkhead box G1B; Forkhead box protein G1; Forkhead box protein G1A; Forkhead box protein G1B; Forkhead box protein G1C; Forkhead drosophila homolog like 2; Forkhead like 1; Forkhead like 2; FOXG1_HUMAN.
PropertiesIf you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.HRP conjugates are often primary rabbit polyclonal antibodies couples to the enzyme horseradish peroxidase (HRP), found in the roots of horseradish. Also monoclonal HRP conjugates are often used for Western Blot.
Additional conjugationHRP Conjugated
French translationanticorps